Marsh bought her ticket from her local Kroger store in Abingdon, Virginia, and returned there on Thursday to pick up her winner's check.
Speaking to Virginia Lottery officials Marsh explained how she felt when she discovered her lucky numbers had done it again.
"I was numb," Marsh recalled. "I just said, 'Hey Dan [her partner], I'm a millionaire.'"
Mega Millions is the biggest jackpot game in America. Jackpots start at $15 million and other prizes range from $1 to $1 million. Drawings are held Tuesdays and Fridays at 23:00 (ET). The next drawing is on Tuesday, September 30, 2014. The estimated jackpot is $105 million.